ADV is not a new virus. Scientists discovered its existence half a century ago. It is in fact one of the most common pathogens that cause colds.

PART 01

What is ADV?

ADV is a group of viruses that infect human mucosa. Depending on the serotype, the virus can cause respiratory symptoms, diarrhea, eye irritation, and rash. ADV infections occur throughout the year.

Different serotypes of ADV can cause different symptoms, such as respiratory tract infections like cough, runny nose, sore throat, and fever; intestinal infections like abdominal pain and diarrhea; and eye infections (commonly known as pink eye). Children, the elderly, and people with compromised immune systems are more susceptible to infections.

ADV is transmitted mainly through droplets (e.g. coughing or sneezing), direct contact with nasal and oral secretions (e.g. shaking hands with the patient or touching contaminated surfaces), or eating contaminated food or water; and can cause outbreaks of acute respiratory and eye infections in institutions such as schools and hospitals.

PART 02

What are the symptoms of the infection?

ADV can cause infections of the respiratory tract, gastrointestinal tract, urinary tract, bladder, eyes, liver, and other organ systems. The population is generally susceptible and is commonly seen between the ages of 6 months and 5 years, especially in children under 2 years old.

Common clinical symptoms include fever, cough, nasal congestion, sore throat, conjunctivitis, abdominal pain, diarrhea, etc. Urinary tract infections may present with symptoms such as haematuria, urinary frequency and urgency, and difficulty in urination.

ADV infection is a self-limiting disease and there is no specific medicine available. Mild cases can heal on their own in a week or so, so do not abuse drugs.

PART 03

Early recognition of severe ADV pneumonia is important

Adenoviral pneumonia most commonly occurs between the ages of 6 months and 5 years, especially in children under 2 years of age. Those with chronic underlying disease and impaired immune function (e.g. organ transplantation, HIV infection, primary immunodeficiency) are more susceptible to severe disease.

Early recognition of the disease based on clinical presentation is important before pathogenic diagnosis, with prompt pathogenic testing, isolation measures, and appropriate empirical treatment.

If there is a local case of ADV infection with high fever lasting more than 3 days, pallor, poor mental response, rales in the lungs, and increased heart rate, be on high alert for the possibility of the disease and get an early pathogenic test for early diagnosis.

PART 04

Rapid identification of ADV

It is very important for outpatient and emergency patients to quickly report the results, preferably within one hour, and within 24 hours for hospitalized patients. It is very important to do a good job in the detection of etiology, which can be targeted medication or symptomatic and supportive treatment, and at the same time is conducive to the rational use of antibacterial drugs.

Hecin focuses on the diagnosis of respiratory system pathogens, and the ADV Nucleic Acid Test Kit (PCR-fluorescence probe method) developed by Hecin has obtained the EU CE certification. This kit can detect common types of adenovirus in respiratory tract infection with a sensitivity of up to 0.22TCID50/ml (type 7), 0.13TCID50/ml (type 3), and can be adapted to common PCR instruments on the market. PCR amplification time among similar products shortest. This product is used to detect adenovirus nucleic acid in oral and throat swab samples. The detectable types cover 17 serotypes of ADV 1~7, 8, 11~14, 35, 39~41, and 55. Early diagnosis of viral infection to avoid missed detection. In addition, in response to the demand for precise detection, to help clinicians accurately determine the recent adenovirus pathogenic subtypes, and to deeply understand the harm of different adenovirus typing, our company has developed adenovirus typing reagents for research and use.

Hecin will give full play to its advantages in technology and products, strive to improve the "accuracy" and "accessibility" of respiratory pathogen detection and help build a precise diagnosis and treatment system.